August 4, 2022 - Bioinformatics

3 things every biologist should know about p-values

Many of us feel out of our comfort zone when we talk about p-values. Here we line up some of our favourite facts about p-values.
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Sequence clusters displaying cell stages and isotypes for class-switching analysis July 12, 2022 - Bioinformatics

Single-cell sequencing and analyzing 10x data

In this article we focus on 10x Genomics single-cell sequence analysis and analyze single B-cell sequences from a paper by King et al. (2021, doi: 10.1126/sciimmunol.abe6291).
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July 1, 2022 - Press release

Press release: TrueBinding and PipeBio announce ongoing collaboration

PipeBio helps TrueBinding power antibody discovery research aimed to find cures for diseases with unmet medical needs, including neurodegenerative diseases (AD, PD, ALS), stroke, metabolic diseases and oncology
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Sanger sequencing analysis with PipeBio

An overview of Sanger tools and workflows on PipeBio Sanger sequencing has been routinely used to characterize immune cell populations and analyze antibody repertoires for more than twenty years. Despite...
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How to analyze 1.6 billion sequences of NGS data in a day

Taking NGS data analysis one step further We are excited to share the latest advancements of PipeBio’s capabilities, as it takes analyzing NGS data one step further. Currently, our customers...
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May 6, 2022 - BioTechPipeBio

Single-cell sequencing technologies in antibody research

Introduction With the current advancements in antibody drug discovery, there is an increasing demand for sequencing technologies to provide efficient tools able to characterize single immunological cells. Single-cell methods offer...
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April 21, 2022 - BioTech

PHAGE-ATAC: a novel approach for rapid nanobody generation

Many sequencing technologies have been developed to characterize the cell state including RNA-seq, ATAC-seq, and ChIP-seq. It has become highly desirable to apply multiple techniques to the same cell. PHAGE-ATAC...
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March 22, 2022 - PipeBioProduct

Selecting antibodies with phage display technology

Introduction Phage display is a powerful technology widely used for identification and selection of peptides binding to a broad range of targets. Since its first demonstration in 1985, the method...
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January 28, 2022 - PipeBio

Identify sequence candidates from biopanning

A key question in therapeutic antibody drug discovery is how to identify the most promising sequence candidates from a biopanning experiment using next-generation sequencing (NGS) data. This can easily be...
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Data Driven Decision Making in Biologics Drug Discovery

In biologics drug discovery, a biomolecule from its origins to the candidate drug status undergoes a variety of characterizations. Such characterizations are aimed to define the effectiveness, specificity, potency, adverse...
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