Automate workflows to identify candidate sequences from large-scale NGS antibody repertoires, hybridoma sequencing, find enriched clonotypes from biopanning experiments or identify liabilities and assess developability of individual Sanger-sequenced clones.
Identify CDRs, mutations towards germline for IgG, scFv, VHH, TCRs or other custom scaffolds for any species. Flag any sequence-based liabilities. Align sequences to identify conserved residues and variability.
Cluster by defining your clonotype, identify clonal families and compare samples across experiments, analyze enrichment and explore clusters visually with cluster network plots.
Use interactive charts to visualize sequence clusters, amino acid frequencies, codons and genes, sequence quality, phylogeny of antibody clones etc.
Associate your functional assay data or metadata with sequences and analyze protein properties, ELISA, structural liabilities, transcriptomics and hit pick your
Edit your sequences on a nucleotide or protein level, use our antibody engineering tools to calculate protein properties, optimize degenerate codons for synthesis, analyze hydrophobicity of sequences and more.
Integrate your ELN or LIMS, internal tools, upload and download data programmatically and build entire automated pipelines through our REST API.
In silico and in vitro methods, data, and machine learning approaches in antibody discovery and engineering research.
PipeBio has rolled out many exciting features in 2022 and in this article we summarized a few of those