Analyzing NGS or Sanger antibody sequences from biopanning and phage, yeast or mammalian display experiments on PipeBio
Identifying clonal families and similar antibodies
Cluster around Sanger sequences and pick developable antibodies from NGS repertoire sequencing
Clustering around characterized hit antibody
You can seed individual clusters from original hit antibodies that have shown target-specificity, in order to find closely related sequences with similar binding properties
Use your characterized antibody clones as a centroid sequence and cluster together with NGS repertoire sequences
Find related, developable sequences with less liabilities from the NGS repertoire with clustering and phylogenetic analysis
