Blog - ngs

Clonal hit expansion by mining antibodies in large NGS repertoires

How to use known target-specific antibodies to find related clones from next-generation repertoire sequencing data NGS is often used to explore the depths of the immune response against a given...
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March 22, 2022 - PipeBioProduct

Selecting antibodies with phage display technology

Introduction Phage display is a powerful technology widely used for identification and selection of peptides binding to a broad range of targets. Since its first demonstration in 1985, the method...
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September 28, 2021 - PipeBio

Nanobodies – A potent alternative

Introduction Biologic drugs are increasingly becoming important as therapeutics for treatment of various diseases, including cancer, infectious and inflammatory diseases. Classical antibody scaffolds and structures are being challenged by smaller...
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September 20, 2021 - PipeBio

Download Original files from PipeBio

When data is uploaded to PipeBio, we parse it and display the results to users. Sequence and related data can then be exported in a wide range of common bioinformatic...
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August 8, 2021 - BioTech

LIBRA-seq: accelerating antibody discovery

With the increased throughput of single cell platforms and sequencing of immune repertoires, new challenges arise and the ability to map individual antibodies to antigens is becoming increasingly important.  What...
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August 8, 2021 - BioTech

NGS, Sanger & PacBio sequencing in Antibody Drug Discovery

Biologics are becoming the drugs of choice when targeting cancers, infectious diseases etc. Monoclonal antibodies have taken up 6 out of 10 of the top selling drugs in the latter...
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