Blog - PipeBio

Clonal hit expansion by mining antibodies in large NGS repertoires

How to use known target-specific antibodies to find related clones from next-generation repertoire sequencing data NGS is often used to explore the depths of the immune response against a given...
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Sanger sequencing analysis with PipeBio

An overview of Sanger tools and workflows on PipeBio Sanger sequencing has been routinely used to characterize immune cell populations and analyze antibody repertoires for more than twenty years. Despite...
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How to analyze 1.6 billion sequences of NGS data in a day

Taking NGS data analysis one step further We are excited to share the latest advancements of PipeBio’s capabilities, as it takes analyzing NGS data one step further. Currently, our customers...
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May 6, 2022 - BioTechPipeBio

Single-cell sequencing technologies in antibody research

Introduction With the current advancements in antibody drug discovery, there is an increasing demand for sequencing technologies to provide efficient tools able to characterize single immunological cells. Single-cell methods offer...
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March 22, 2022 - PipeBioProduct

Selecting antibodies with phage display technology

Introduction Phage display is a powerful technology widely used for identification and selection of peptides binding to a broad range of targets. Since its first demonstration in 1985, the method...
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January 28, 2022 - PipeBio

Identify sequence candidates from biopanning

A key question in therapeutic antibody drug discovery is how to identify the most promising sequence candidates from a biopanning experiment using next-generation sequencing (NGS) data. This can easily be...
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Data Driven Decision Making in Biologics Drug Discovery

In biologics drug discovery, a biomolecule from its origins to the candidate drug status undergoes a variety of characterizations. Such characterizations are aimed to define the effectiveness, specificity, potency, adverse...
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September 28, 2021 - PipeBio

Nanobodies – A potent alternative

Introduction Biologic drugs are increasingly becoming important as therapeutics for treatment of various diseases, including cancer, infectious and inflammatory diseases. Classical antibody scaffolds and structures are being challenged by smaller...
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September 20, 2021 - PipeBio

Download Original files from PipeBio

When data is uploaded to PipeBio, we parse it and display the results to users. Sequence and related data can then be exported in a wide range of common bioinformatic...
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September 14, 2021 - PipeBio

Isogenica-PipeBio Collaboration Press Release

Isogenica announce deployment of the PipeBio Bioinformatic Cloud SEP 9, 2021 Isogenica today announce that they are deploying PipeBio’s bioinformatic cloud to accelerate their drug discovery efforts in the field of therapeutic...
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