Introduction With the current advancements in antibody drug discovery, there is an increasing demand for sequencing technologies to provide efficient tools able to characterize single immunological cells. Single-cell methods offer a deep insight into the complex biology of the immune system and enable the precise study of cell secretion, migration, cell-to-cell interaction and mRNA sequencing.… Continue reading Single-cell sequencing technologies in antibody research
Author: Max Gubert Olivé
PHAGE-ATAC: a novel approach for rapid nanobody generation
Many sequencing technologies have been developed to characterize the cell state including RNA-seq, ATAC-seq, and ChIP-seq. It has become highly desirable to apply multiple techniques to the same cell. PHAGE-ATAC runs single cell ATAC-seq and mitochondrial DNA sequencing while also detecting intracellular epitopes. One key application of PHAGE-ATAC is the rapid generation of antigen specific… Continue reading PHAGE-ATAC: a novel approach for rapid nanobody generation
Selecting antibodies with phage display technology
Introduction Phage display is a powerful technology widely used for identification and selection of peptides binding to a broad range of targets. Since its first demonstration in 1985, the method has been proven extremely successful in a variety of fields, such as protein engineering, drug discovery, medical diagnosis and therapeutic targeting. The principle of phage… Continue reading Selecting antibodies with phage display technology